Miro3D® Three-Dimensional Wound Matrix
Reprise Biomedical Miro3D® · applied by Apollo Wound Care
Some wounds are not a surface — they are a space. A flat sheet graft laid over a deep, tunnelling or undermined wound leaves dead space underneath it, and dead space is where healing stalls. Miro3D is different in kind: a 2 cm-thick, open-porous acellular scaffold that is trimmed at the bedside to the shape of the defect and packed into it, holding contact with the wound's walls and base instead of just its rim. It is made from porcine liver — chosen because the liver is the body's most densely vascularised organ, so once its cells are washed out the collagen left behind is a naturally open, interconnected three-dimensional network rather than a flat plane. Host tissue then grows into that open structure from the surrounding wound.
Three measurable effects on the wound.
Fill the dead space
At 2 cm thick the matrix is a volume, not a film. Trimmed to the defect, it occupies the cavity a flat graft would bridge over — the space where deep wounds stall.
Hold contact with walls and base
Cut to shape so it sits in maximum possible contact with healthy, well-vascularised tissue — the sides and floor of the wound, not only the surface rim.
Let tissue grow in
The scaffold stays open and porous so host tissue can integrate into it. Once it has integrated it is deliberately left in place rather than stripped back out.
The problem it exists to solve.
Every other product here treats a wound as a surface. A deep, tunnelling or undermined wound is not a surface — it is a cavity, and a flat graft laid across the top leaves the space underneath empty. Dead space is where drainage collects, bacteria settle and healing stalls, and it is precisely the wound type that defeats ordinary care. Miro3D is the only thing in the bag that fills that volume, which is why carrying it changes which wounds can be taken on at home at all.
Treats depth, which flat products cannot
At 2 cm thick and trimmed to shape, it occupies the cavity rather than bridging it — closing the dead space where deep wounds stall.
Contact with walls and base, not just the rim
Cut to the defect so it meets healthy tissue on every surface it touches, which is what gives the wound something to grow into from all sides.
It stays put and becomes part of the repair
Host tissue grows into the open structure, and once integrated it is deliberately left in place — so progress is not undone by pulling the material back out.
Trimmed to your wound at the bedside
Ten sizes from 8 cm³ to 100 cm³, cut to the shape of the defect during a home visit — the wound sets the size, not the packaging.
What the data shows.
In plain language.
- Built for wounds with depth — cavities, tunnels and undermined edges a flat dressing can bridge over.
- The scaffold is trimmed to fit your wound during a normal home visit and packed into the space.
- Once your own tissue grows into it, it is left in place rather than removed.
- Used for partial- and full-thickness wounds, ulcers, tunnelled and undermined wounds and surgical wounds.
Miro3D® is a registered trademark of Reprise Biomedical, Inc.; Albacete MedDev is an independent distributor and not the manufacturer. FDA 510(k) cleared (K221520) for partial- and full-thickness wounds, ulcers, tunnelled and undermined wounds and surgical wounds. Published clinical experience is limited to a small retrospective case series (Abdo & Couch, J Wound Care 2024;33(Sup9):S5–S16), a single-case report and conference material — there are no randomised or comparative results, and larger trials are enrolling but have not reported. Contraindicated in patients with known sensitivity to porcine material and not indicated for third-degree burns; not applied until infection, bleeding and excessive exudate are controlled. Candidacy and coverage are determined at clinical assessment.
Your wound won't wait. Neither do we.
One phone call covers everything: the wound, your insurance, and the first visit date. Family members and referring providers are welcome to call on a patient's behalf.
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